Mechanism and contraindications of Nandrolone Decanoate Injection

Spread the love

Nandrolone Decanoate is an anabolic type of steroid whose uses are mainly for treating anemiaand osteoporosis. It is also known to increase the amount of hemoglobin in the body along with the red cell mass. Before taking this injection, you should know about its working and its contradictions. Learn the basic of Nandrolone decanoate.

Mechanism of Action

Nandrolone decanoate has the same action as that of testosterone. The exogenous androgens like the nandrolone decanoatepromote the anabolism of protein that stimulates the appetite resulting in the reversal of the catabolic processes and also the balance of negative nitrogen. It also results in an increased lean mass of the body with patients suffering from cachexia (for instance, malnourished patients on dialysis) and also the decrease in bone resorption and also the increased number of bone density in patients having osteoporosis which are noted down.

Androgens also affect the balance of calcium, blood glucose,anderythrocyte production.  When the production of erythropoietic stimulating factor increases, it results in the increase in erythrocyte production. For patients who are suffering from anemia are associated with renal disease, they have an increased level of the volume of red blood cells and higher hemoglobin after they receive the dosage of nandrolone decanoate.

Nandrolone Decanoate

Since the action of nandrolone decanoate is similar to that of the endogenous androgens, the administration of the nandrolone decanoate is possible if using some serious disturbances in the sexual development if it is prescribed to given to the children leading to cause unavoidableadverse effects on women, mainly. The hormone which releases gonadotropin is suppressed by exogenous androgens, resulting in the reduced number of the functions of the gonadotropicactuator via the negative feedback mechanism. This reduces the endogenous testosterone, the LH,and the FSH. The testes can be directly affected by the exogenousand the androgens. The reversible increasesthe low-density lipoproteins (LDL) and alsoresult in the decreases in high-density lipoproteins (HDL).

There are also some of the contraindications to look out for:

  • Pregnancy

The contraindication of the Nandrolone decanoate is done during the period of pregnancy as it affects the fetus. Androgenic anabolic steroids also causeembryo toxicity, female animal offspring’s masculinization. It is also contradicted in the women who are pregnant or are going to be pregnant. Using nandrolone decanoate in the pregnancy periodor if pregnancy occurs during the intake of this steroid, she must have caused the fetus some sort of hazard.

  • Breastfeeding

It is yet to be discovered whether human milk excretes anabolic steroids or not. Nandrolone does not indicate the potential of female childbearing. Its use while breastfeeding must be avoided because it could result in some of the most adverse reaction in the infants who are still nursing. It is recommended to use other alternative methods for breastfeeding.


Consultancy with the doctor or physician is recommended before the use of this steroid. You should be very careful about the dosage and intake it only at the doctors advise. Failing to do so will lead to various hazards of the body.